Tolucombi 80mg/12.5mg Tables
Keep out of reach of children. Red the manual carefully before use
If need more information please consult with your doctor
THERAPEUTIC INDICATION:
Treatment of essential hypertension.
Tolucombi fixed dose combination is indicated in adults whose blood pressure is not adequately controlled on telmisartan alone
DOSAGE AND METHOD OF ADMINISTRATION:
Dosage:
Tolucombi should be used in patients whose blood pressure is not adequately controlled on telmisartan alone. It is recommended to individually titrate the dose of each component before switching to a fixed combination. When clinically justified, a direct switch from monotherapy to a fixed combination may be considered.
Tolucombi 80 mg / 12.5 mg can be given once daily to patients whose blood pressure cannot be adequately controlled on telmisartan 80 mg.
Patients with renal impairment
Periodic monitoring of renal function is advised
Patients with hepatic impairment
In patients with mild to moderate hepatic impairment, the daily dose of one Tolucombi 40 mg / 12.5 mg tablet should not be exceeded. Tolucombi is not indicated in patients with severe hepatic impairment. Thiazides should be used with caution in patients with hepatic
Elderly patients
No dose adjustment is required.
Pediatric population
The efficacy and safety of Tolucombi in children and adolescents under 18 years of age have not been established. No data available.
Method of application:
Tolucombi tablets should be taken once a day with liquid, with or without food.
Contraindications
Hypersensitivity to the active substances or to any of the excipients of this drug. Hypersensitivity to other substances of sulfonamide derivatives (since hydrochlorothiazide is a sulfonamide derivative).
Second and third trimesters of pregnancy. Cholestasis and biliary obstructive disorders.
Severe liver failure.
OTHER INFORMATION: Please refer to the Instruction sheet included in the package
MANUFACTURED BY: KRKA, D.D., NOVO MESTO (SLOVENIA)
DISTRIBUTOR: GLOBAL PHARMACEUTICAL JOINT-STOCK COMPANY
