NICARLOL ® PLUS
Keep out of reach of children. Read the manual carefully before use
If need more information please consult with your doctor
THERAPEUTIC INDICATION:
Treatment of essential hypertension.
POSOLOGY AND METHOD OF ADMINISTRATION:
Posology:
Adults
The dose is one tablet (5 mg/12.5 mg) daily, preferably at the same time of the day. Tablets may be taken with meals.
Elderly: In view of the limited experience in patients above 75 years, caution must be exercised and these patients monitored closely
Renal impairment : Should not be given to patients with severe renal insufficiency
Hepatic impairment: Data in patients with hepatic insufficiency or impaired liver function are limited. Therefore the use of Nicarlol in these patients is contraindicated.
Paediatric population: The efficacy and safety of Nicarlol in children and adolescents aged below 18 years has not been established. No data are available. Therefore, use in children and adolescents is not recommended.
Method of administration:
Oral use. Tablets may be taken with meals
CONTRAINDICATIONS:
Hypersensitivity to the active substances or to any of the excipients
Hypersensitivity to other sulphonamide-derived substances (since hydrochlorothiazide is a sulphonamide-derived medicinal product).
Liver insufficiency or liver function impairment.
Anuria, severe renal insufficiency (creatinine clearance < 30 ml/min.).
Acute heart failure, cardiogenic shock or episodes of heart failure decompensation requiring intravenous inotropic therapy.
Sick sinus syndrome, including sino-atrial block.
Second and third-degree atrioventricular block (without a pacemaker).
Bradycardia (heart rate < 60 bpm prior to starting therapy).
Hypotension (systolic blood pressure < 90 mmHg).
Severe peripheral circulatory disturbances.
History of bronchospasm and bronchial asthma.
Untreated phaeochromocytoma.
Metabolic acidosis.
Refractory hypokalaemia, hypercalcaemia, hyponatraemia and symptomatic hyperuricaemia
OTHER INFORMATION: Please refer to the Instruction sheet included in the package
MANUFACTURED BY: AGIMEXPHARM PHARMACEUTICAL JOINT STOCK COMPANY
DISTRIBUTOR: GLOBAL PHARMACEUTICAL JOINT STOCK COMPANY
